TIGER Study

The Investigation of Genetic Exome Research (TIGER Study)

In the TIGER research study, we are learning more about individuals with genetic events associated with autism spectrum disorder (ASD), intellectual disability (ID), and/or developmental delay (DD) in order to better describe how different gene disruptions impact behavior in children and adults. Individuals with these genetic changes may have neurodevelopmental differences that we would like to better understand.

Families who participate in the TIGER study will be able to help us further scientific knowledge of these rare genetic events through either remote participation or an in-person visit. Participation will include clinical phone interviews, questionnaires, photos, and a blood draw. For in-person visits, we may also complete neurocognitive assessments, EEG, 3-dimensional photos, language testing, a medical examination, and optional skin biopsy. Expenses related to the study visit (such as the blood draw or lodging) will be covered by the study and subjects will be reimbursed $100 for their participation.

Families identified with changes in the same genes can choose to be connected with each other to allow them to form support groups. The study team is also committed to keeping participating families up to date with any new information that they might find interesting or helpful.

Families who are interested in learning more, or would like to participate, can contact the study team:

  • Phone: 206-221-2147
  • Email: Morgan: This email address is being protected from spambots. You need JavaScript enabled to view it.

Who can participate? 

Children (4 years and older) with a change in one of the genes listed below:

ADNP

ANK2

CHD2

CHD8

CTNNB1

DSCAM

DYRK1A

FOXP1

GRIN2B

MBD5

MED13L

POGZ

SCN2A

SUV420H1

TBR1

TRIP12