TIGER Study

The Investigation of Genetic Exome Research (TIGER Study)

The University of Washington’s Autism Center is performing a study to better understand the medical, learning, and behavioral features of individuals with genetic changes in the genes of interest listed below, identified through exome sequencing. 

In this study, subjects (ages 4 and up) and their parents will be seen for two day in-person visit at the University of Washington. During the visit, the subjects undergo a diagnostic evaluation, language testing, motor assessments, blood draw, EEG, medical exam, and an optional skin biopsy. Parents are asked to complete a few interviews and questionnaires. Parents also meet with members of the study team to discuss the goals of the study, how their child's participation helps with research, and to answer any questions the parents may have about participation. After the visit, families are provided with a written report with feedback about the visit findings which may be helpful for educational planning. Expenses related to participation are covered by the study (travel, accommodations, food).

Families identified with changes in the same genes can choose to be connected with each other to allow them to form support groups. The study team is also committed to keeping participating families up to date with any new information that they might find interesting or helpful.

Families who are interested in learning more, or would like to participate, can contact the study team:

  • Phone: 206-616-2889
  • Email: Alanna: This email address is being protected from spambots. You need JavaScript enabled to view it. or General Inquiries: This email address is being protected from spambots. You need JavaScript enabled to view it.

Who can participate? 

Children (4 years and older) with a change in one of the genes listed below:

ADNP

ANK2

ARID1B

CHD1

CHD2

CHD8

CTNNB1

CTTNBP2

DSCAM

DYRK1A

FOXP1

GRIN2B

KDM6B

LARP4B

MBD5

MED13L

NCKAP1

PARD3B

POGZ

PTEN

SCN2A

SETBP1

SETD2

STXBP1

TBL1XR1

TBR1

TCF7L2

WAC

WDFY3

WDR33

ZMYND11